Endocrine Abstracts

Introduction: Hypertension is a very common chronic disease worldwide. Its imbalance is one of the main causes of cardiovascular and neurodegenerative complications.Patients and Methods: We collected data from hypertensive patients who voluntarily presented for screening on both diabetes and hypertension screening days.Poor blood pressure control was defined as systolic blood pressure (SBP) greater than or equal to 140 mmHg and/or diastolic blood pressur...

Introduction: Central precocious puberty (CPP) is a frequent reason for consultation in pediatrics. It is defined as the development of sexual characteristics before the age of 8 years in girls and 9 years in boys. Pediatric pituitary adenomas are rare. We report the case of a patient who presented with central precocious puberty on pituitary adenoma.Observation: This is a patient aged 7 years and 6 months, without any particular history, having consulte...

Introduction: Hashimoto’s encephalopathy or SREAT (steroid-responsive encephalopathy associated with auto-immune thyroiditis) is a rare autoimmune disorder that is particularly corticosensitive and whose pathogenesis remains poorly understood. It is associated with high levels of antithyroid antibodies in plasma and/or CSF. Clinical manifestations are deceptive and may include cognitive and behavioral disturbances, seizures or abnormal movements.Cas...

Introduction: Refractory hypothyroidism is a fairly common situation in the practice of any endocrinologist, being defined by the persistence of hypothyroidism despite adequate doses of replacement therapy with Levothyroxine, generally supraphysiological. We report the case of refractory hypothyroidism under high doses of Levothyroxine.Observation: she was a 54-year-old woman, diabetic Type2, followed for 06 years for papillary carcinoma of the thyroid g...

Introduction: Thevenard’s disease is a sensory neuropathy with a type of ulcerative-mutilating acropathy of progressive course. It has a hereditary character with autosomal dominant inheritance. It is a scarce disease, which usually affects feet but can also affect hands. It causes disorders of thermoalgesic sensitivity, leading to painless ulcerations at the pressure points and then bone deformities with osteoarticular destruction and ‘cubic foot‘ appearance. R...

Introduction: Bariatric surgery was shown to treat obesity and decrease cardiovascular risk such as metabolic syndrome, diabetes, and hypertension. In individuals living with HIV, bariatric surgery can alter oral bioavailability of anti-viral therapy through its impact on the intestinal pH, intestinal transit time and first pass mechanism. This can have adverse impact on CD4 count and viral load (VL). Nevertheless, numerous studies highlight that bariatric surgery does not hav...

Turner syndrome (TS) is the most common chromosomal anomaly in females and its occurrence is about 1:4000 live births. This is the only monomer disease that humans can survive (1). It is characterized by the presence of one X chromosome and a partial or complete loss of the second X chromosome. Clinical features of TS can vary, mainly classified into Growth failure, gonadal insufficiency, cardiovascular diseases, or learning disabilities. Short stature is the only phenotypic a...

Introduction: Autoimmune thyroid diseases are frequent and very polymorphic pathologies. The same person can successively present with different manifestations. Graves’ disease and Hashimoto’s thyroiditis seem to be able to coexist. The name "Hashitoxicosis" has been suggested in this case, characterized by the sequential association, whatever the order, of hyper- and hypothyroidism. We report in this work, the case of a patient treated for autoimmune hypothy...

Introduction: Enzyme block is a rare disorder that can be discovered at birth by a severe, life-threatening disorder or in a more attenuated form in adulthood by a clinical picture of hyperandrogenism most often. The enzyme block most commonly suspected in high blood pressure is 11 B OH blockWe report the case of a young patient who was diagnosed with 21 hydroxylase enzyme block by secondary hypertension testing.Observation: This is a 32 year old patient...

Background: Graves’ disease (GD) is the commonest cause of primary hyperthyroidism in iodine-sufficient areas. First-line treatment is a 12-18 month course of anti-thyroid drugs (ATD). However, around 50% of GD patients will relapse, requiring further assessment and definitive treatment with radioactive iodine or thyroidectomy. Identifying risk factors that predict relapse or treatment failure after stopping ATD is important in guiding management. Several risk factors hav...